Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis
نویسندگان
چکیده
منابع مشابه
Infection, inflammation and colon carcinogenesis
Citation Wogan, G.N. et al. "Infection, inflammation and colon carcinogenesis. The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters.
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The flavone 4',5,7-trihydroxy-3',5'-dimethoxyflavone (tricin) present in rice, oats, barley, and wheat exhibits antigrowth activity in several human cancer cell lines and anti-inflammatory potential. However, the chemopreventive activity has not yet been elucidated in preclinical animal models of colorectal cancer. This study was designed to determine whether dietary tricin exerts inflammation-...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2014
ISSN: 0021-9738
DOI: 10.1172/jci69672